Ginkgo Leaf Terpenoids

INCI: GINKGO LEAF TERPENOIDS

CAS Number
107438-79-9, 15291-75-5, 15291-76-6, 15291-77-7, 33570-04-6 (ginkgolides A/B/C/J + bilobalide)
Function
Antimicrobial, antioxidant, hair conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited or restricted under 21 CFR; CIR concluded data insufficient (2024); antiacne/antifungal/analgesic claims fall outside cosmetic purview

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Isolated terpenoids carry lower alkylphenol risk than crude extracts, but CIR requires composition and impurity data to confirm purification removes ginkgolic acids; bilobalide has neurotoxic potential at high systemic doses; PAT inhibition properties documented; no 28-day dermal study available

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Concern Level: High

Frequently Asked Questions

Is Ginkgo Leaf Terpenoids safe in cosmetics?

Isolated terpenoids carry lower alkylphenol risk than crude extracts, but CIR requires composition and impurity data to confirm purification removes ginkgolic acids; bilobalide has neurotoxic potential at high systemic doses; PAT inhibition properties documented; no 28-day dermal study available The EU classifies Ginkgo Leaf Terpenoids as "permitted". Safety rating: MODERATE.

Is Ginkgo Leaf Terpenoids allowed in the EU?

Ginkgo Leaf Terpenoids EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginkgo Leaf Terpenoids do in cosmetics?

Ginkgo Leaf Terpenoids functions as: Antimicrobial, antioxidant, hair conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 107438-79-9, 15291-75-5, 15291-76-6, 15291-77-7, 33570-04-6 (ginkgolides A/B/C/J + bilobalide).

What is the Margin of Safety for Ginkgo Leaf Terpenoids?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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