Ginseng Extract (Panax Ginseng Root Extract)

INCI: PANAX GINSENG ROOT EXTRACT

CAS Number
84650-12-4
Function
Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted without restriction. Strong market presence in K-beauty and premium anti-aging segments. Topical ginsenoside efficacy supported by in-vitro and some clinical data. MoCRA safety substantiation required.

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Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Ginseng extract offers strong in-vitro evidence for cosmetic use with documented MMP-1 inhibition and procollagen synthesis stimulation via ginsenosides. Clinical performance is well-established in K-beauty contexts, though robust independent RCTs for topical use remain limited. Fermented ginseng shows enhanced bioavailability. Antioxidant and collagen-support claims can be substantiated from available in-vitro data.

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Concern Level: Low

Regulatory Flags

adaptogen antioxidant anti-aging collagen-synthesis k-beauty holistic-beauty mmp-inhibitor

Frequently Asked Questions

Is Ginseng Extract (Panax Ginseng Root Extract) safe in cosmetics?

Ginseng extract offers strong in-vitro evidence for cosmetic use with documented MMP-1 inhibition and procollagen synthesis stimulation via ginsenosides. Clinical performance is well-established in K-beauty contexts, though robust independent RCTs for topical use remain limited. Fermented ginseng shows enhanced bioavailability. Antioxidant and collagen-support claims can be substantiated from available in-vitro data. The EU classifies Ginseng Extract (Panax Ginseng Root Extract) as "permitted". Safety rating: GOOD.

Is Ginseng Extract (Panax Ginseng Root Extract) allowed in the EU?

Ginseng Extract (Panax Ginseng Root Extract) EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginseng Extract (Panax Ginseng Root Extract) do in cosmetics?

Ginseng Extract (Panax Ginseng Root Extract) functions as: Extract from Panax ginseng roots. Active constituents: ginsenosides (steroidal saponins with antioxidant, anti-inflammatory, and collagen-stimulating activity), polysaccharides (hydration), and polyacetylenes. Mechanisms: ginsenosides inhibit MMP-1 (collagen-degrading enzyme) and stimulate procollagen synthesis in fibroblasts; antioxidant via free-radical scavenging; brightening via inhibition of melanin synthesis.. It is classified as a Active Ingredient in our database. CAS number: 84650-12-4.

What is the Margin of Safety for Ginseng Extract (Panax Ginseng Root Extract)?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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