Ginsenoside Rd

INCI: GINSENOSIDE RD

CAS Number
52705-93-8
Function
Skin conditioning, antioxidant (constituent of Panax ginseng root extract)
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not prohibited or restricted under 21 CFR; covered under CIR Panax spp. assessment (safe as used, 2015)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Harmfulness code R22 (harmful if swallowed) at neat chemical grade; cosmetic use concentrations are trace-level as a minor ginsenoside. Estrogenic activity reported in vitro—consider in products for pregnant/nursing populations.

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Concern Level: Low

Frequently Asked Questions

Is Ginsenoside Rd safe in cosmetics?

Harmfulness code R22 (harmful if swallowed) at neat chemical grade; cosmetic use concentrations are trace-level as a minor ginsenoside. Estrogenic activity reported in vitro—consider in products for pregnant/nursing populations. The EU classifies Ginsenoside Rd as "permitted". Safety rating: GOOD.

Is Ginsenoside Rd allowed in the EU?

Ginsenoside Rd EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginsenoside Rd do in cosmetics?

Ginsenoside Rd functions as: Skin conditioning, antioxidant (constituent of Panax ginseng root extract). It is classified as a cosmetic ingredient in our database. CAS number: 52705-93-8.

What is the Margin of Safety for Ginsenoside Rd?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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