Is Ginsenoside Rd safe in cosmetics?
Ginsenoside Rd has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Ginsenoside Rd
Also known as: β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-, (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, 3-O-β-D-Glucopyranosyl-(1→2)-β-D-glucopyranosyl-20-O-β-D-glucopyranosyldammar-24-ene-3β,12β,20S-triol, 2-O-β-D-glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-β-D-glucopyranoside, EC No.: 258-118-5 (+6 more)
INCI: GINSENOSIDE RD
Ginsenoside Rd (CAS 52705-93-8) is a cosmetic cosmetic ingredient functioning as Skin conditioning, antioxidant (constituent of Panax ginseng root extract). EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 52705-93-8 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning, antioxidant (constituent of Panax ginseng root extract)
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S,3R,4S,5S,6R)-2-[(2R,3R,4S,5S,6R)-4,5-dihydroxy-6-(hydroxymethyl)-2-[[(3S,5R,8R,9R,10R,12R,13R,14R,17S)-12-hydroxy-4,4,8,10,14-pentamethyl-17-[(2S)-6-methyl-2-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhept-5-en-2-yl]-2,3,5,6,7,9,11,12,13,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]oxy]oxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol
InChIKey
RLDVZILFNVRJTL-IWFVLDDISA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — not prohibited or restricted under 21 CFR; covered under CIR Panax spp. assessment (safe as used, 2015)
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Ginsenoside Rd.
Calculate MoS for your specific formulation with the MoS Calculator.
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Antioxidant
Expert Verdict
Expert safety assessment and concern-level summary for Ginsenoside Rd.
Known Synonyms
β-D-Glucopyranoside, (3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-
(3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside
3-O-β-D-Glucopyranosyl-(1→2)-β-D-glucopyranosyl-20-O-β-D-glucopyranosyldammar-24-ene-3β,12β,20S-triol
2-O-β-D-glucopyranosyl-(3β,12β)-20-(β-D-glucopyranosyloxy)-12-hydroxydammara-24-en-3-yl-β-D-glucopyranoside
EC No.: 258-118-5
Chikusetsusaponin FK7
Dammarane, β-D-glucopyranoside deriv.
Ginsenoside Rd1
Gypenoside VIII
258-118-5
EINECS 258-118-5
Chemical Function
Antioxidant
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
Compound
GINSENOSIDE RD
ChEMBL ID
CHEMBL473659
Max Phase
3
Frequently Asked Questions
Is Ginsenoside Rd allowed in the EU?
Ginsenoside Rd EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Ginsenoside Rd do in cosmetics?
Ginsenoside Rd functions as: Skin conditioning, antioxidant (constituent of Panax ginseng root extract). It is classified as a cosmetic ingredient in our database. CAS number: 52705-93-8.
Is Ginsenoside Rd used outside cosmetics?
Ginsenoside Rd also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
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Ingredient Decoder
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Substance Compliance
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MoS Calculator
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Heavy Metal Limits
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