Ginsenoside Re

INCI: GINSENOSIDE RE

CAS Number
52286-59-6
Function
Skin conditioning, antioxidant (major protopanaxatriol-type ginsenoside)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited or restricted under 21 CFR; covered under CIR Panax spp. assessment (safe as used, 2015)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

One of the most abundant ginsenosides in raw ginseng with well-documented anti-inflammatory and antioxidant properties; estrogenic activity reported; oral LD50 data available but dermal-specific LD50 not published.

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Concern Level: Low

Frequently Asked Questions

Is Ginsenoside Re safe in cosmetics?

One of the most abundant ginsenosides in raw ginseng with well-documented anti-inflammatory and antioxidant properties; estrogenic activity reported; oral LD50 data available but dermal-specific LD50 not published. The EU classifies Ginsenoside Re as "permitted". Safety rating: GOOD.

Is Ginsenoside Re allowed in the EU?

Ginsenoside Re EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Ginsenoside Re do in cosmetics?

Ginsenoside Re functions as: Skin conditioning, antioxidant (major protopanaxatriol-type ginsenoside). It is classified as a cosmetic ingredient in our database. CAS number: 52286-59-6.

What is the Margin of Safety for Ginsenoside Re?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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