Glucomannan Hydroxypropyltrimonium Chloride

INCI: GLUCOMANNAN HYDROXYPROPYLTRIMONIUM CHLORIDE

CAS Number
Not uniquely assigned (structurally related to Guar Hydroxypropyltrimonium Chloride, CAS 65497-29-2)
Function
Antistatic, hair conditioning, hair fixing, viscosity controlling
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not restricted under 21 CFR; CIR Panel concluded galactomannans (including hydroxypropyltrimonium chloride derivatives) safe as used

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Cationic quaternary ammonium moiety may cause mild ocular irritation at elevated concentrations; ensure concentrations are consistent with CIR-reviewed use levels (โ‰ค 0.05% in sprays/powders)

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Concern Level: Moderate

Frequently Asked Questions

Is Glucomannan Hydroxypropyltrimonium Chloride safe in cosmetics?

Cationic quaternary ammonium moiety may cause mild ocular irritation at elevated concentrations; ensure concentrations are consistent with CIR-reviewed use levels (โ‰ค 0.05% in sprays/powders) The EU classifies Glucomannan Hydroxypropyltrimonium Chloride as "permitted". Safety rating: GOOD.

Is Glucomannan Hydroxypropyltrimonium Chloride allowed in the EU?

Glucomannan Hydroxypropyltrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glucomannan Hydroxypropyltrimonium Chloride do in cosmetics?

Glucomannan Hydroxypropyltrimonium Chloride functions as: Antistatic, hair conditioning, hair fixing, viscosity controlling. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (structurally related to Guar Hydroxypropyltrimonium Chloride, CAS 65497-29-2).

What is the Margin of Safety for Glucomannan Hydroxypropyltrimonium Chloride?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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