Glycereth-25 PCA Isostearate

CAS Number
Not individually assigned (UNII: TV85Z17HAZ; CosIng Ref 76276)
Function
Emulsifier; Softener and conditioner
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited or restricted; listed in FDA GSRS (precisionFDA)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Less publicly available safety data than other glycereths; 1,4-dioxane and ethylene oxide impurity risk; PCA moiety is well-tolerated but adds structural complexity requiring supplier-level documentation

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Concern Level: Moderate

Frequently Asked Questions

Is Glycereth-25 PCA Isostearate safe in cosmetics?

Less publicly available safety data than other glycereths; 1,4-dioxane and ethylene oxide impurity risk; PCA moiety is well-tolerated but adds structural complexity requiring supplier-level documentation The EU classifies Glycereth-25 PCA Isostearate as "permitted". Safety rating: MODERATE.

Is Glycereth-25 PCA Isostearate allowed in the EU?

Glycereth-25 PCA Isostearate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycereth-25 PCA Isostearate do in cosmetics?

Glycereth-25 PCA Isostearate functions as: Emulsifier; Softener and conditioner. It is classified as a cosmetic ingredient in our database. CAS number: Not individually assigned (UNII: TV85Z17HAZ; CosIng Ref 76276).

What is the Margin of Safety for Glycereth-25 PCA Isostearate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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