Glyceryl Cocoyl Leucinate

INCI: GLYCERYL COCOYL LEUCINATE

CAS Number
Not established (CosIng entry exists without CAS)
Function
Skin conditioning agent (amino acid–acyl glyceryl derivative)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted; not on FDA prohibited list; no specific CFR citation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major data gap. No genotoxicity, sensitization, irritation, or dermal penetration data found. Amino acid (leucine) and coconut acyl moieties are individually low-concern, but the specific conjugate is untested. Not suitable for CPSR without bespoke testing or robust read-across justification.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Glyceryl Cocoyl Leucinate safe in cosmetics?

Major data gap. No genotoxicity, sensitization, irritation, or dermal penetration data found. Amino acid (leucine) and coconut acyl moieties are individually low-concern, but the specific conjugate is untested. Not suitable for CPSR without bespoke testing or robust read-across justification. The EU classifies Glyceryl Cocoyl Leucinate as "permitted". Safety rating: MODERATE.

Is Glyceryl Cocoyl Leucinate allowed in the EU?

Glyceryl Cocoyl Leucinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Cocoyl Leucinate do in cosmetics?

Glyceryl Cocoyl Leucinate functions as: Skin conditioning agent (amino acid–acyl glyceryl derivative). It is classified as a cosmetic ingredient in our database. CAS number: Not established (CosIng entry exists without CAS).

What is the Margin of Safety for Glyceryl Cocoyl Leucinate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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