Glyceryl Diferulate

INCI: GLYCERYL DIFERULATE

CAS Number
Not established from available databases
Function
Skin conditioning agent, antioxidant (ferulic acid ester)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically addressed by CIR; ferulic acid itself is GRAS (21 CFR 172.515)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No specific HRIPT, genotoxicity, or dermal irritation data for this ester. Read-across from ferulic acid and glycerol components is reasonable but must be formally justified. Hydrolysis kinetics should be characterized. Photostability should be addressed as ferulic acid is a UV absorber with potential for photoallergy if used in sun-exposed products.

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Concern Level: Moderate

Frequently Asked Questions

Is Glyceryl Diferulate safe in cosmetics?

No specific HRIPT, genotoxicity, or dermal irritation data for this ester. Read-across from ferulic acid and glycerol components is reasonable but must be formally justified. Hydrolysis kinetics should be characterized. Photostability should be addressed as ferulic acid is a UV absorber with potential for photoallergy if used in sun-exposed products. The EU classifies Glyceryl Diferulate as "prohibited". Safety rating: MODERATE.

Is Glyceryl Diferulate allowed in the EU?

Glyceryl Diferulate EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Diferulate do in cosmetics?

Glyceryl Diferulate functions as: Skin conditioning agent, antioxidant (ferulic acid ester). It is classified as a cosmetic ingredient in our database. CAS number: Not established from available databases.

What is the Margin of Safety for Glyceryl Diferulate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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