Good Cosmetic Ingredient NOAEL Data

Glyceryl Oleate Citrate

INCI: GLYCERYL OLEATE CITRATE

CAS Number
N/A
Function
Surfactant - cleansing, surfactant - emulsifying (PEG-free anionic O/W emulsifier)
Safety Rating
GOOD

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes No specific FDA restrictions. Mono-/diglyceride class GRAS for food. No dedicated CIR review for this specific INCI.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Toxicological Studies

7 study endpoints found for Glyceryl Oleate Citrate. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.

Endpoint Value Route Species Study Type Source
NOAEL 30 mg/kg bw/day dermal - - SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day - - reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day oral rat reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day oral - reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day dermal - - SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day oral - reproductive SCCS_PDF_extraction
NOAEL 30 mg/kg bw/day - - reproductive SCCS_PDF_extraction

Expert Verdict

Safe based on glyceryl monoester class read-across and GRAS status of constituent moieties.

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Concern Level: Low

Regulatory Flags

eu_children_restricted

Frequently Asked Questions

Is Glyceryl Oleate Citrate safe in cosmetics?

Safe based on glyceryl monoester class read-across and GRAS status of constituent moieties. The EU classifies Glyceryl Oleate Citrate as "permitted". Safety rating: GOOD. 7 toxicological study endpoint(s) are available in our database.

Is Glyceryl Oleate Citrate allowed in the EU?

Glyceryl Oleate Citrate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Oleate Citrate do in cosmetics?

Glyceryl Oleate Citrate functions as: Surfactant - cleansing, surfactant - emulsifying (PEG-free anionic O/W emulsifier). It is classified as a cosmetic ingredient in our database. CAS number: N/A.

What is the Margin of Safety for Glyceryl Oleate Citrate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

What is the NOAEL for Glyceryl Oleate Citrate?

The NOAEL (No Observed Adverse Effect Level) for Glyceryl Oleate Citrate is 30 mg/kg bw/day based on a toxicological study via dermal route in rat. A total of 7 study endpoints are available. Source: SCCS_PDF_extraction.

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