Glyceryl Stearate/Acetate

INCI: GLYCERYL STEARATE/ACETATE

CAS Number
Mixture — no unique CAS; components: Glyceryl Stearate (31566-31-1) + Glyceryl Acetate (26446-35-5)
Function
Skin conditioning agent — emollient, emulsifier
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — Glyceryl Stearate is GRAS (21 CFR 184.1324); Glyceryl Acetate is an indirect food additive (21 CFR 177.1200)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Mixture of two monoesters (Glyceryl Stearate and Glyceryl Acetate) reviewed individually; both components permitted in cosmetics, though Glyceryl Acetate showed positive genotoxicity in vitro requiring confirmation of negative in vivo results.

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Concern Level: Moderate

Frequently Asked Questions

Is Glyceryl Stearate/Acetate safe in cosmetics?

Mixture of two monoesters (Glyceryl Stearate and Glyceryl Acetate) reviewed individually; both components permitted in cosmetics, though Glyceryl Acetate showed positive genotoxicity in vitro requiring confirmation of negative in vivo results. The EU classifies Glyceryl Stearate/Acetate as "permitted". Safety rating: GOOD.

Is Glyceryl Stearate/Acetate allowed in the EU?

Glyceryl Stearate/Acetate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glyceryl Stearate/Acetate do in cosmetics?

Glyceryl Stearate/Acetate functions as: Skin conditioning agent — emollient, emulsifier. It is classified as a cosmetic ingredient in our database. CAS number: Mixture — no unique CAS; components: Glyceryl Stearate (31566-31-1) + Glyceryl Acetate (26446-35-5).

What is the Margin of Safety for Glyceryl Stearate/Acetate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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