Moderate Cosmetic Ingredient

Glycine Max Isoflavones

INCI: GLYCINE MAX ISOFLAVONES

CAS Number
574-12-9 (genistein, primary isoflavone); mixture CAS varies by supplier
Function
Skin conditioning, antioxidant, anti-aging
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific FDA prohibition; however, estrogenic activity is flagged in literature

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Phytoestrogenic activity — genistein and daidzein bind estrogen receptors; potential endocrine disruption concern at high doses. Soy allergen cross-reactivity possible. Some regulatory bodies flag estrogenic cosmetic claims.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Glycine Max Isoflavones safe in cosmetics?

Phytoestrogenic activity — genistein and daidzein bind estrogen receptors; potential endocrine disruption concern at high doses. Soy allergen cross-reactivity possible. Some regulatory bodies flag estrogenic cosmetic claims. The EU classifies Glycine Max Isoflavones as "permitted". Safety rating: MODERATE.

Is Glycine Max Isoflavones allowed in the EU?

Glycine Max Isoflavones EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycine Max Isoflavones do in cosmetics?

Glycine Max Isoflavones functions as: Skin conditioning, antioxidant, anti-aging. It is classified as a cosmetic ingredient in our database. CAS number: 574-12-9 (genistein, primary isoflavone); mixture CAS varies by supplier.

What is the Margin of Safety for Glycine Max Isoflavones?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Glycine Max Isoflavones compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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