Glycol Oleate

INCI: GLYCOL OLEATE

CAS Number
4500-01-0 (mono); 9004-96-0 (polyethoxylated form also cited)
Function
Emollient, surfactant–emulsifying, skin conditioning
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — EPA Safer Chemical (Green Circle); on TSCA inventory

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

GHS H315 (skin irritation) and H319 (eye irritation) reported for neat material at 11.1% and 41.2% of ECHA notifications respectively. At typical cosmetic use levels below 5%, irritation risk is manageable. EPA Safer Choice Green-listed.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Glycol Oleate safe in cosmetics?

GHS H315 (skin irritation) and H319 (eye irritation) reported for neat material at 11.1% and 41.2% of ECHA notifications respectively. At typical cosmetic use levels below 5%, irritation risk is manageable. EPA Safer Choice Green-listed. The EU classifies Glycol Oleate as "permitted". Safety rating: GOOD.

Is Glycol Oleate allowed in the EU?

Glycol Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycol Oleate do in cosmetics?

Glycol Oleate functions as: Emollient, surfactant–emulsifying, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 4500-01-0 (mono); 9004-96-0 (polyethoxylated form also cited).

What is the Margin of Safety for Glycol Oleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Glycol Oleate in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Glycol Oleate in your formulation.