Is Glycyl Tyrosine safe in cosmetics?
Glycyl Tyrosine has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Good
Cosmetic Ingredient
Glycyl Tyrosine
Also known as: N-Glycyltyrosine, (2S)-2-[(2-Azaniumylacetyl)amino]-3-(4-hydroxyphenyl)propanoate
INCI: GLYCYL TYROSINE
Glycyl Tyrosine (CAS 658-79-7) is a cosmetic cosmetic ingredient functioning as Skin conditioning; dipeptide with potential antioxidant and anti-melanogenic. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in industrial chemical safety and pharmaceutical data.
View industrial chemical safety profile for CAS 658-79-7 →
Auto-generated CPSR Part A draft with source citations
Function
Skin conditioning; dipeptide with potential antioxidant and anti-melanogenic properties
Safety Rating
GOOD
Chemistry & Identifiers
IUPAC Name
(2S)-2-[(2-aminoacetyl)amino]-3-(4-hydroxyphenyl)propanoic acid
InChIKey
XBGGUPMXALFZOT-VIFPVBQESA-N
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
Permitted — no CFR restriction; not specifically CIR-reviewed
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Glycyl Tyrosine.
Calculate MoS for your specific formulation with the MoS Calculator.
ECHA REACH Registration
European Chemicals Agency REACH dossier and Substances of Very High Concern listing.
Registration Type
Full
Tonnage Band
1 - 10 tonnes
Substance Type
SUBSTANCE
SVHC Candidate
No
Expert Verdict
Expert safety assessment and concern-level summary for Glycyl Tyrosine.
Regulatory Flags
natural-origin
Known Synonyms
N-Glycyltyrosine
(2S)-2-[(2-Azaniumylacetyl)amino]-3-(4-hydroxyphenyl)propanoate
Cross-Vertical Safety Context
Same-CAS public records found in pharmaceutical data.
SOURCE
ChEMBL / DrugCentral / FAERS
DB_PHARMA CAS match
Pharmaceutical Data
Same-CAS rows from the pharmaceutical spoke database.
ChEMBL ID
CHEMBL53400
Frequently Asked Questions
Is Glycyl Tyrosine allowed in the EU?
Glycyl Tyrosine EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Glycyl Tyrosine do in cosmetics?
Glycyl Tyrosine functions as: Skin conditioning; dipeptide with potential antioxidant and anti-melanogenic properties. It is classified as a cosmetic ingredient in our database. CAS number: 658-79-7.
Is Glycyl Tyrosine used outside cosmetics?
Glycyl Tyrosine also appears in industrial chemical safety and pharmaceutical data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Glycyl Tyrosine compliance across multiple jurisdictions:
Ingredient Decoder
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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