Glycyrrhiza Inflata Root Extract

INCI: FORMULATORS SHOULD MONITOR GLYCYRRHIZIC ACID CONCENTRATION IN THE FINAL PRODUCT, PARTICULARLY WHEN COMBINING MULTIPLE LICORICE-DERIVED INGREDIENTS IN A SINGLE FORMULA, AS CUMULATIVE EXPOSURE COULD INCREASE SENSITIZATION OR ENDOCRINE-ACTIVITY RISK. <SPAN STYLE="DISPLAY:NONE"></SPAN>

CAS Number
Not specifically assigned in CosIng (distinct species from G. glabra)
Function
Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed - no prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains licochalcone A as the predominant bioactive (rather than glycyrrhizin dominant in G. glabra); generally well-tolerated topically; limited long-term safety data compared to G. glabra. The key differentiator from G. glabra is high licochalcone A content, which inhibits 5-alpha-reductase (reducing sebum production), provides bacteriostatic activity, and exhibits superoxide dismutase-like antioxidant action; particularly effective for oily and acne-prone skin

โš ๏ธ
Concern Level: Moderate

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Glycyrrhiza Inflata Root Extract safe in cosmetics?

Contains licochalcone A as the predominant bioactive (rather than glycyrrhizin dominant in G. glabra); generally well-tolerated topically; limited long-term safety data compared to G. glabra. The key differentiator from G. glabra is high licochalcone A content, which inhibits 5-alpha-reductase (reducing sebum production), provides bacteriostatic activity, and exhibits superoxide dismutase-like antioxidant action; particularly effective for oily and acne-prone skin The EU classifies Glycyrrhiza Inflata Root Extract as "permitted". Safety rating: MODERATE.

Is Glycyrrhiza Inflata Root Extract allowed in the EU?

Glycyrrhiza Inflata Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Glycyrrhiza Inflata Root Extract do in cosmetics?

Glycyrrhiza Inflata Root Extract functions as: Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not specifically assigned in CosIng (distinct species from G. glabra).

What is the Margin of Safety for Glycyrrhiza Inflata Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

๐Ÿ“ฑ

Is Glycyrrhiza Inflata Root Extract in Your Products?

Scan any product label with Piro โ€” our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free โ†’

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Glycyrrhiza Inflata Root Extract in your formulation.