Guanidine Ferulamide

INCI: GUANIDINE FERULAMIDE

CAS Number
Not readily available (guanidine salt/amide of ferulic acid)
Function
Skin conditioning agent derived from guanidine and ferulic acid
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted by default, not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No CIR review or SCCS opinion available. While ferulic acid has a strong safety profile, the guanidine conjugate lacks independent safety assessment and requires in vitro irritation and sensitization testing including DPRA, KeratinoSens, and h-CLAT.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Guanidine Ferulamide safe in cosmetics?

No CIR review or SCCS opinion available. While ferulic acid has a strong safety profile, the guanidine conjugate lacks independent safety assessment and requires in vitro irritation and sensitization testing including DPRA, KeratinoSens, and h-CLAT. The EU classifies Guanidine Ferulamide as "permitted". Safety rating: MODERATE.

Is Guanidine Ferulamide allowed in the EU?

Guanidine Ferulamide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Guanidine Ferulamide do in cosmetics?

Guanidine Ferulamide functions as: Skin conditioning agent derived from guanidine and ferulic acid. It is classified as a cosmetic ingredient in our database. CAS number: Not readily available (guanidine salt/amide of ferulic acid).

What is the Margin of Safety for Guanidine Ferulamide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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