Is Guar Gum Hydroxypropyltrimonium Chloride safe in cosmetics?
Guar Gum Hydroxypropyltrimonium Chloride has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
Guar Gum Hydroxypropyltrimonium Chloride
Also known as: UNII-B16G315W7A
INCI: GUAR HYDROXYPROPYLTRIMONIUM CHLORIDE
Guar Gum Hydroxypropyltrimonium Chloride (CAS 65497-29-2) is a cosmetic cosmetic ingredient functioning as Hair conditioning, antistatic, skin conditioning. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database. Same-CAS public records also appear in food safety data.
View industrial chemical safety profile for CAS 65497-29-2 →
Function
Hair conditioning, antistatic, skin conditioning
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR concluded safe as used in cosmetics; no FDA restrictions; widely used in shampoos and conditioners
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Guar Gum Hydroxypropyltrimonium Chloride.
Calculate MoS for your specific formulation with the MoS Calculator.
Dermal Penetration Profile
Skin absorption and penetration characteristics of Guar Gum Hydroxypropyltrimonium Chloride, relevant to systemic exposure and MoS calculations.
Absorption %
0%
Penetration Level
surface
Penetration Depth
surface only
Molecular Weight
Variable Da
Log P
n/a
Systemic Absorption
no
Topical Bioavailability
0%
Safety Margin Factor
none
Source: CIR Expert Panel
Typical Use Concentrations
Reported concentration ranges per product category from SCCS/CIR/industry sources.
| Product Category | Typical Range | Max Reported | Source |
|---|---|---|---|
| Shampoo | 0.1–0.5 | 1 | CIR Safety Assessment |
| Conditioner | 0.1–0.5 | 1 | CIR Safety Assessment |
Function Categories & List Membership
Cosmetic/Chemical Function Categories
Anti-adhesive/cohesive
Anti-static agent
Film former
Softener and conditioner
Thickening agent
Viscosity modifier
Regulatory List Membership (1)
EU Regulated in Personal Care
Editorial summary
Preliminary editorial summary for Guar Gum Hydroxypropyltrimonium Chloride — not a computed safety verdict. See the sourced toxicological data above.
Regulatory Flags
cationic-polymer
hair-conditioning
antistatic
plant-derived
Known Synonyms
UNII-B16G315W7A
Chemical Function
Film former
Anti-static agent
Softener and conditioner
Viscosity modifier
Regulatory Lists
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care - hair styling and care - shampoo-dandruff
Europe; Personal care
Europe; Personal care
Europe; Personal care
Australian Status
AICIS status: listed
Cross-Vertical Safety Context
Same-CAS public records found in food safety data.
SOURCE
EFSA / FDA GRAS
food_additives
Food Safety Data
Same-CAS food additive or FDA GRAS records from the core public database.
Food Name
Gum ghatti
E Number
E419
ADI
NO ADI ALLOCATED mg/kg bw
Food Category
emulsifier
Frequently Asked Questions
Is Guar Gum Hydroxypropyltrimonium Chloride allowed in the EU?
Guar Gum Hydroxypropyltrimonium Chloride EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Guar Gum Hydroxypropyltrimonium Chloride do in cosmetics?
Guar Gum Hydroxypropyltrimonium Chloride functions as: Hair conditioning, antistatic, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 65497-29-2.
Is Guar Gum Hydroxypropyltrimonium Chloride used outside cosmetics?
Guar Gum Hydroxypropyltrimonium Chloride also appears in food safety data. The cross-vertical cards on this page render same-CAS public rows from the matched databases.
Compliance Tools
Check Guar Gum Hydroxypropyltrimonium Chloride compliance across multiple jurisdictions:
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82 Allergen Checker
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
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