NOAEL Studies Cosmetic Ingredient

HC Blue No. 11 NOAEL Studies

INCI: HC BLUE NO. 11

CAS: 910463-51-3

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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SCCS Opinion 7 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
SCCS Opinion NOAEL =160 mg/kg bw/day - - - NOAEL study p.14
SCCS Opinion NOAEL =80 mg/kg bw/day - - - NOAEL study p.14
SCCS Opinion NOAEL =200 mg/kg bw/day human - - developmental toxicity p.19
SCCS Opinion NOAEL =0.046 mg/kg bw rat oral 90day dermal absorption p.20
SCCS Opinion NOAEL =80 mg/kg bw rat oral 90day dermal absorption p.20
SCCS Opinion NOAEL =1275 mg/kg bw rat oral subchronic repeated dose toxicity p.20
SCCS Opinion NOAEL =100 mg/kg bw rat oral subchronic repeated dose toxicity p.20
Regulatory source 8 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source - 160 mg/kg bw/day - - - - p.14
Regulatory source - 80 mg/kg bw/day - - - - p.14
Regulatory source dermal absorption =0.046 mg/kg bw rat oral 90day dermal absorption p.20
Regulatory source dermal absorption =80 mg/kg bw rat oral 90day dermal absorption p.20
Regulatory source developmental toxicity 200 mg/kg bw/day human - - developmental toxicity p.19
Regulatory source repeated dose toxicity 1275 mg/kg bw rat oral subchronic repeated dose toxicity p.20
Regulatory source repeated dose toxicity 80 mg/kg bw/day rat oral subchronic repeated dose toxicity p.20
Regulatory source repeated dose toxicity 100 mg/kg bw rat oral subchronic repeated dose toxicity p.20
openFDA substances 1 endpoint
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
openFDA substances FDA UNII substance identifier 83ZYM95HPE UNII - - - chemical -