Moderate Cosmetic Ingredient

Heptapeptide-14

INCI: HEPTAPEPTIDE-14

CAS Number
Not publicly assigned (commonly supplied as Copper Palmitoyl Heptapeptide-14)
Function
Skin conditioning agent
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted, not restricted

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Copper-complexed form may require trace metal documentation for CPSR; confirm whether product uses free peptide or Copper Palmitoyl Heptapeptide-14 as regulatory and safety profiles differ. Clinical studies report 33% wrinkle reduction and 19% elasticity increase in 28-day trials.

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Concern Level: Moderate

Frequently Asked Questions

Is Heptapeptide-14 safe in cosmetics?

Copper-complexed form may require trace metal documentation for CPSR; confirm whether product uses free peptide or Copper Palmitoyl Heptapeptide-14 as regulatory and safety profiles differ. Clinical studies report 33% wrinkle reduction and 19% elasticity increase in 28-day trials. The EU classifies Heptapeptide-14 as "permitted". Safety rating: MODERATE.

Is Heptapeptide-14 allowed in the EU?

Heptapeptide-14 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Heptapeptide-14 do in cosmetics?

Heptapeptide-14 functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly assigned (commonly supplied as Copper Palmitoyl Heptapeptide-14).

What is the Margin of Safety for Heptapeptide-14?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Heptapeptide-14 compliance across multiple jurisdictions:

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Ingredient Decoder
Paste a full ingredient list for instant analysis
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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