Heptapeptide-33

INCI: HEPTAPEPTIDE-33 (DERIVATIVE: CAPRYLOYL HEPTAPEPTIDE-33)

CAS Number
Not publicly listed
Function
Anti-sebum, antimicrobial, antioxidant, skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted; allowed under general cosmetics provisions

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

No SCCS opinion; no published safety alerts. Most functionally diverse of this entire group - uniquely assigned anti-sebum and antimicrobial functions in addition to skin conditioning and antioxidant activity. The capryloyl derivative adds caprylic acid (octanoic acid) for enhanced delivery.

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Concern Level: Moderate

Frequently Asked Questions

Is Heptapeptide-33 safe in cosmetics?

No SCCS opinion; no published safety alerts. Most functionally diverse of this entire group - uniquely assigned anti-sebum and antimicrobial functions in addition to skin conditioning and antioxidant activity. The capryloyl derivative adds caprylic acid (octanoic acid) for enhanced delivery. The EU classifies Heptapeptide-33 as "permitted". Safety rating: MODERATE.

Is Heptapeptide-33 allowed in the EU?

Heptapeptide-33 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Heptapeptide-33 do in cosmetics?

Heptapeptide-33 functions as: Anti-sebum, antimicrobial, antioxidant, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not publicly listed.

What is the Margin of Safety for Heptapeptide-33?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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