Hexahydro-Methanoindene-5-ylidene-2-Butanol

INCI: HEXAHYDRO-METHANOINDENE-5-YLIDENE-2-BUTANOL

CAS Number
Not conclusively confirmed — structurally analogous to Bacdanol® (CAS 28219-61-6) or related sandalwood replacers
Function
Fragrance (sandalwood/creamy/woody character)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Not specifically restricted under 21 CFR 700

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Health Canada has flagged certain synthetic sandalwood fragrances as potential sensitizers. Canada's assessment covered structurally related compounds. The exocyclic double bond (ylidene) may form reactive metabolites. Full toxicological dossier recommended.

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Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Hexahydro-Methanoindene-5-ylidene-2-Butanol safe in cosmetics?

Health Canada has flagged certain synthetic sandalwood fragrances as potential sensitizers. Canada's assessment covered structurally related compounds. The exocyclic double bond (ylidene) may form reactive metabolites. Full toxicological dossier recommended. The EU classifies Hexahydro-Methanoindene-5-ylidene-2-Butanol as "permitted". Safety rating: MODERATE.

Is Hexahydro-Methanoindene-5-ylidene-2-Butanol allowed in the EU?

Hexahydro-Methanoindene-5-ylidene-2-Butanol EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexahydro-Methanoindene-5-ylidene-2-Butanol do in cosmetics?

Hexahydro-Methanoindene-5-ylidene-2-Butanol functions as: Fragrance (sandalwood/creamy/woody character). It is classified as a cosmetic ingredient in our database. CAS number: Not conclusively confirmed — structurally analogous to Bacdanol® (CAS 28219-61-6) or related sandalwood replacers.

What is the Margin of Safety for Hexahydro-Methanoindene-5-ylidene-2-Butanol?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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