Hexahydropropenyloxy-methanoindene

INCI: HEXAHYDROPROPENYLOXY-METHANOINDENE

CAS Number
Not definitively confirmed in available databases — structurally a propenyloxy analog within the hexahydro-methanoindene fragrance family
Function
Perfuming (fragrance ingredient)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no CFR restriction identified; no standalone CIR or RIFM assessment located

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical data gap exists. The propenyloxy moiety introduces α,β-unsaturated ether functionality, warranting evaluation for potential Michael-acceptor reactivity and skin sensitization risk. Read-across from the methoxy analog may be attempted but must be formally justified in a CPSR. RIFM/ECHA dossier review and in-silico alert screening recommended before formulation use.

⚠️
Concern Level: Moderate

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Hexahydropropenyloxy-methanoindene safe in cosmetics?

Critical data gap exists. The propenyloxy moiety introduces α,β-unsaturated ether functionality, warranting evaluation for potential Michael-acceptor reactivity and skin sensitization risk. Read-across from the methoxy analog may be attempted but must be formally justified in a CPSR. RIFM/ECHA dossier review and in-silico alert screening recommended before formulation use. The EU classifies Hexahydropropenyloxy-methanoindene as "permitted". Safety rating: MODERATE.

Is Hexahydropropenyloxy-methanoindene allowed in the EU?

Hexahydropropenyloxy-methanoindene EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hexahydropropenyloxy-methanoindene do in cosmetics?

Hexahydropropenyloxy-methanoindene functions as: Perfuming (fragrance ingredient). It is classified as a cosmetic ingredient in our database. CAS number: Not definitively confirmed in available databases — structurally a propenyloxy analog within the hexahydro-methanoindene fragrance family.

What is the Margin of Safety for Hexahydropropenyloxy-methanoindene?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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