Is Hexapeptide-12 safe in cosmetics?
Hexapeptide-12 has a safety rating of "GOOD" in our database. EU status: permitted. US status: permitted.
GOOD
Cosmetic Ingredient
Hexapeptide-12
INCI: HEXAPEPTIDE-12
Hexapeptide-12 (CAS Not assigned for base peptide (Palmitoyl Hexapeptide-12 has supplier-specific identifiers)) is a cosmetic cosmetic ingredient functioning as Skin Conditioning — elastin-derived peptide with defined sequence. EU Regulation 1223/2009 status: permitted. Industrial safety data is also available in the chemical safety database.
CAS Number
Not assigned for base peptide (Palmitoyl Hexapeptide-12 has supplier-specific identifiers)
View industrial chemical safety profile →
Function
Skin Conditioning — elastin-derived peptide with defined sequence Val-Gly-Val-Ala-Pro-Gly
Editorial assessment
GOOD
Preliminary editorial note — not a computed safety verdict.
Regulatory Status
EU EU Status
permitted
US US Status
permitted
US Notes
CIR-reviewed safe in present practices of use and concentration
For full compliance data across multiple jurisdictions, use the Substance Compliance tool.
Safety Data
Margin of Safety, dermal absorption, and sensitization profile summaries for Hexapeptide-12.
Calculate MoS for your specific formulation with the MoS Calculator.
Editorial summary
Preliminary editorial summary for Hexapeptide-12 — not a computed safety verdict. See the sourced toxicological data above.
Frequently Asked Questions
Is Hexapeptide-12 allowed in the EU?
Hexapeptide-12 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hexapeptide-12 do in cosmetics?
Hexapeptide-12 functions as: Skin Conditioning — elastin-derived peptide with defined sequence Val-Gly-Val-Ala-Pro-Gly. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned for base peptide (Palmitoyl Hexapeptide-12 has supplier-specific identifiers).
Compliance Tools
Check Hexapeptide-12 compliance across multiple jurisdictions:
Ingredient Decoder
Paste a full ingredient list for instant analysis
82 Allergen Checker
Check for EU declarable fragrance allergens
Substance Compliance
Check compliance across multiple jurisdictions
MoS Calculator
Calculate Margin of Safety using SCCS methodology
Heavy Metal Limits
Compare limits across jurisdictions
Is Hexapeptide-12 in Your Products?
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Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hexapeptide-12 in your formulation.