Holothuria Scabra Extract

INCI: HOLOTHURIA SCABRA EXTRACT

CAS Number
Not assigned in major cosmetic databases
Function
Skin conditioning, antioxidant (DPPH and NO scavenging demonstrated in formulation studies)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not specifically regulated. Could be used as a cosmetic ingredient under FDCA general provisions, but MoCRA requires full safety substantiation

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Major data gaps with no CIR, SCCS, or CosIng listing. Marine-sourced ingredient raises CITES/sustainability concerns, heavy metal bioaccumulation risk, and potential marine allergen issues. CPSR would require substantial supplier-provided toxicology data. Not suitable for GMP-ready formulation without a comprehensive safety dossier.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Holothuria Scabra Extract safe in cosmetics?

Major data gaps with no CIR, SCCS, or CosIng listing. Marine-sourced ingredient raises CITES/sustainability concerns, heavy metal bioaccumulation risk, and potential marine allergen issues. CPSR would require substantial supplier-provided toxicology data. Not suitable for GMP-ready formulation without a comprehensive safety dossier. The EU classifies Holothuria Scabra Extract as "permitted". Safety rating: MODERATE.

Is Holothuria Scabra Extract allowed in the EU?

Holothuria Scabra Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Holothuria Scabra Extract do in cosmetics?

Holothuria Scabra Extract functions as: Skin conditioning, antioxidant (DPPH and NO scavenging demonstrated in formulation studies). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in major cosmetic databases.

What is the Margin of Safety for Holothuria Scabra Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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