NOAEL Studies Cosmetic Ingredient

Houttuynia Cordata Leaf/Stem Extract NOAEL Studies

INCI: HOUTTUYNIA CORDATA LEAF/STEM EXTRACT

CAS: 164288-50-0

Raw No Observed Adverse Effect Level endpoint records grouped by source. This page does not render calculated Margin of Safety values.

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CIR Safety Assessment 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
CIR Safety Assessment NOAEL =250 mg/kg/d rat oral Subchronic repeated dose toxicity 5; 28; (6, p.5
CIR Safety Assessment NOAEL =350 mg/kg/d rat - 2-wk developmental toxicity 17; 2; (6, p.5
Regulatory source 2 endpoints
Source Endpoint Type Value Unit Species Route Duration Study Type Reference
Regulatory source developmental toxicity 350 mg/kg/d rat - 2-wk developmental toxicity p.5
Regulatory source repeated dose toxicity 250 mg/kg/d rat oral Subchronic repeated dose toxicity p.5