Hydrolyzed Camellia Sinensis Leaf

INCI: HYDROLYZED CAMELLIA SINENSIS LEAF

CAS Number
Not uniquely assigned (parent leaf extract CAS 84650-60-2)
Function
Skin conditioning agent — humectant
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Camellia sinensis preparations are GRAS (21 CFR 182.20); no cosmetic-specific restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Caffeine content (2.5–4.2% dry weight) requires monitoring for cumulative exposure when combined with other tea-derived ingredients. Quercetin demonstrates positive in vitro genotoxicity in Ames assay but negative in vivo oral genotoxicity; formulation must ensure nonsensitizing profile per CIR requirements.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydrolyzed Camellia Sinensis Leaf safe in cosmetics?

Caffeine content (2.5–4.2% dry weight) requires monitoring for cumulative exposure when combined with other tea-derived ingredients. Quercetin demonstrates positive in vitro genotoxicity in Ames assay but negative in vivo oral genotoxicity; formulation must ensure nonsensitizing profile per CIR requirements. The EU classifies Hydrolyzed Camellia Sinensis Leaf as "permitted". Safety rating: GOOD.

Is Hydrolyzed Camellia Sinensis Leaf allowed in the EU?

Hydrolyzed Camellia Sinensis Leaf EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Camellia Sinensis Leaf do in cosmetics?

Hydrolyzed Camellia Sinensis Leaf functions as: Skin conditioning agent — humectant. It is classified as a cosmetic ingredient in our database. CAS number: Not uniquely assigned (parent leaf extract CAS 84650-60-2).

What is the Margin of Safety for Hydrolyzed Camellia Sinensis Leaf?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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