Hydrolyzed Human Placental Protein

INCI: HYDROLYZED HUMAN PLACENTAL PROTEIN

CAS Number
91080-01-2 (general placental protein hydrolysate)
Function
Skin conditioning agent
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Insufficient data โ€” CIR Final Report concluded data are insufficient to support safety; additional sensitization, repeated-dose, repro/dev tox, genotoxicity, and photosensitization studies are needed

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

CIR deemed unsafe with current data; EU-prohibited; human-origin disease transmission risk; estrogenic and biologically active substance concerns; incompatible with COSMOS/ECOCERT certification

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Concern Level: High

Frequently Asked Questions

Is Hydrolyzed Human Placental Protein safe in cosmetics?

CIR deemed unsafe with current data; EU-prohibited; human-origin disease transmission risk; estrogenic and biologically active substance concerns; incompatible with COSMOS/ECOCERT certification The EU classifies Hydrolyzed Human Placental Protein as "prohibited". Safety rating: POOR.

Is Hydrolyzed Human Placental Protein allowed in the EU?

Hydrolyzed Human Placental Protein EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Human Placental Protein do in cosmetics?

Hydrolyzed Human Placental Protein functions as: Skin conditioning agent. It is classified as a cosmetic ingredient in our database. CAS number: 91080-01-2 (general placental protein hydrolysate).

What is the Margin of Safety for Hydrolyzed Human Placental Protein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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