Hydrolyzed Placental Extract

INCI: HYDROLYZED PLACENTAL EXTRACT

CAS Number
Not assigned
Function
Skin conditioning (historically claimed anti-aging, cell-renewal activity)
Safety Rating
POOR

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status prohibited
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with major caveats. FDA Cosmetic Handbook explicitly flags placental extracts; any estrogenic or hormonal claim triggers drug classification.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Critical INCI ambiguity with species not specified; EU assessors will challenge origin documentation. CIR identified 5 missing data categories (sensitization, repeat-dose dermal, photosensitization, genotoxicity, ocular toxicity). TSE/viral contamination risk if animal-origin; estrogenic activity must be ruled out for any market.

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Concern Level: High

Regulatory Flags

plant-extract potential-allergen

Frequently Asked Questions

Is Hydrolyzed Placental Extract safe in cosmetics?

Critical INCI ambiguity with species not specified; EU assessors will challenge origin documentation. CIR identified 5 missing data categories (sensitization, repeat-dose dermal, photosensitization, genotoxicity, ocular toxicity). TSE/viral contamination risk if animal-origin; estrogenic activity must be ruled out for any market. The EU classifies Hydrolyzed Placental Extract as "prohibited". Safety rating: POOR.

Is Hydrolyzed Placental Extract allowed in the EU?

Hydrolyzed Placental Extract EU regulatory status: prohibited. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Placental Extract do in cosmetics?

Hydrolyzed Placental Extract functions as: Skin conditioning (historically claimed anti-aging, cell-renewal activity). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned.

What is the Margin of Safety for Hydrolyzed Placental Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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