Hydrolyzed Polygonum Multiflorum Root Extract
INCI: HYDROLYZED POLYGONUM MULTIFLORUM ROOT EXTRACT
Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Expert Verdict
Hepatotoxicity well-documented for oral ingestion; R62/R63 phrases assigned to pharmaceutical-grade extract indicating possible reproductive toxicity risk; teratogenicity in zebrafish embryos above 225 mg/L; emodin and anthraquinone content may cause phototoxicity. Essential to control emodin levels and conduct phototoxicity testing. Assessor should demand supplier CoA specifying anthraquinone limits.
Regulatory Flags
Frequently Asked Questions
Is Hydrolyzed Polygonum Multiflorum Root Extract safe in cosmetics?
Hepatotoxicity well-documented for oral ingestion; R62/R63 phrases assigned to pharmaceutical-grade extract indicating possible reproductive toxicity risk; teratogenicity in zebrafish embryos above 225 mg/L; emodin and anthraquinone content may cause phototoxicity. Essential to control emodin levels and conduct phototoxicity testing. Assessor should demand supplier CoA specifying anthraquinone limits. The EU classifies Hydrolyzed Polygonum Multiflorum Root Extract as "permitted". Safety rating: POOR.
Is Hydrolyzed Polygonum Multiflorum Root Extract allowed in the EU?
Hydrolyzed Polygonum Multiflorum Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrolyzed Polygonum Multiflorum Root Extract do in cosmetics?
Hydrolyzed Polygonum Multiflorum Root Extract functions as: Antioxidant, hair conditioning, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned for hydrolyzed form; parent extract CAS 2972-94-3.
What is the Margin of Safety for Hydrolyzed Polygonum Multiflorum Root Extract?
not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
Compliance Tools
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