Hydrolyzed Proanthocyanidin

INCI: HYDROLYZED PROANTHOCYANIDIN

CAS Number
Not assigned; CosIng Ref No. 56576
Function
Antioxidant, humectant, skin conditioning – emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — grape seed proanthocyanidins have GRAS status for food; no FDA restriction for cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

China restricts use to 0.2% in leave-on whole-body products and 0.005% in eye-area leave-on products; botanical source (grape, pine bark, etc.) must be specified as composition varies; astringent properties may cause dryness at high concentrations; generally well-supported by food-safety and supplement literature

⚠️
Concern Level: Low

Regulatory Flags

natural-origin

Frequently Asked Questions

Is Hydrolyzed Proanthocyanidin safe in cosmetics?

China restricts use to 0.2% in leave-on whole-body products and 0.005% in eye-area leave-on products; botanical source (grape, pine bark, etc.) must be specified as composition varies; astringent properties may cause dryness at high concentrations; generally well-supported by food-safety and supplement literature The EU classifies Hydrolyzed Proanthocyanidin as "permitted". Safety rating: GOOD.

Is Hydrolyzed Proanthocyanidin allowed in the EU?

Hydrolyzed Proanthocyanidin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Proanthocyanidin do in cosmetics?

Hydrolyzed Proanthocyanidin functions as: Antioxidant, humectant, skin conditioning – emollient. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned; CosIng Ref No. 56576.

What is the Margin of Safety for Hydrolyzed Proanthocyanidin?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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