Regulatory Status
For full compliance data across 55 jurisdictions, use the Substance Compliance tool.
Safety Data
Calculate MoS for your specific formulation with the MoS Calculator.
Toxicological Studies
2 study endpoints found for Hydrolyzed Reticulin. NOAEL (No Observed Adverse Effect Level) values are used to calculate the Margin of Safety per SCCS methodology.
| Endpoint | Value | Route | Species | Study Type | Source |
|---|---|---|---|---|---|
| NOAEL | >1000 mg/kg bw/day | oral | rat | oral | REACH |
| NOAEL | >1000 mg/kg bw/day | oral | - | oral | REACH |
Expert Verdict
BSE/TSE compliance mandatory (animal connective tissue source). Requires species declaration, country of origin, CEP or equivalent TSE risk assessment. CIR conclusion supports safety when properly sourced.
Frequently Asked Questions
Is Hydrolyzed Reticulin safe in cosmetics?
BSE/TSE compliance mandatory (animal connective tissue source). Requires species declaration, country of origin, CEP or equivalent TSE risk assessment. CIR conclusion supports safety when properly sourced. The EU classifies Hydrolyzed Reticulin as "permitted". Safety rating: GOOD. 2 toxicological study endpoint(s) are available in our database.
Is Hydrolyzed Reticulin allowed in the EU?
Hydrolyzed Reticulin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.
What does Hydrolyzed Reticulin do in cosmetics?
Hydrolyzed Reticulin functions as: Hair conditioning; skin conditioning (hydrolysate of reticulin / type III collagen from animal connective tissue). It is classified as a cosmetic ingredient in our database. CAS number: 99924-37-5.
What is the Margin of Safety for Hydrolyzed Reticulin?
adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.
What is the NOAEL for Hydrolyzed Reticulin?
The NOAEL (No Observed Adverse Effect Level) for Hydrolyzed Reticulin is >1000 mg/kg bw/day based on a oral study via oral route in rat. A total of 2 study endpoints are available. Source: REACH.
Compliance Tools
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Related Ingredients
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