Hydrolyzed Rheum Officinale Root Extract

INCI: HYDROLYZED RHEUM OFFICINALE ROOT EXTRACT

CAS Number
84650-56-6
Function
Skin protecting (hydrolysate of roots of Chinese Rhubarb, Rheum officinale, Polygonaceae)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited/restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Anthraquinone content is the primary concern due to emodin genotoxicity flags in in vitro studies; CPSR assessor should require anthraquinone quantification by HPLC, phototoxicity testing, and use-level justification.

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Concern Level: High

Regulatory Flags

plant-extract

Frequently Asked Questions

Is Hydrolyzed Rheum Officinale Root Extract safe in cosmetics?

Anthraquinone content is the primary concern due to emodin genotoxicity flags in in vitro studies; CPSR assessor should require anthraquinone quantification by HPLC, phototoxicity testing, and use-level justification. The EU classifies Hydrolyzed Rheum Officinale Root Extract as "permitted". Safety rating: MODERATE.

Is Hydrolyzed Rheum Officinale Root Extract allowed in the EU?

Hydrolyzed Rheum Officinale Root Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydrolyzed Rheum Officinale Root Extract do in cosmetics?

Hydrolyzed Rheum Officinale Root Extract functions as: Skin protecting (hydrolysate of roots of Chinese Rhubarb, Rheum officinale, Polygonaceae). It is classified as a cosmetic ingredient in our database. CAS number: 84650-56-6.

What is the Margin of Safety for Hydrolyzed Rheum Officinale Root Extract?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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