Hydroxydaidzein

INCI: HYDROXYDAIDZEIN

CAS Number
485-63-2
Function
Antioxidant, skin conditioning, skin protecting
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no specific CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Endocrine disruptor concern with ongoing SCCS re-evaluation for isoflavones. Genotoxic potential not excluded for daidzein; phytoestrogen activity documented. Genistein cleared at โ‰ค0.007% but hydroxydaidzein lacks individual concentration limit. Use with caution pending final SCCS opinion.

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Concern Level: High

Frequently Asked Questions

Is Hydroxydaidzein safe in cosmetics?

Endocrine disruptor concern with ongoing SCCS re-evaluation for isoflavones. Genotoxic potential not excluded for daidzein; phytoestrogen activity documented. Genistein cleared at โ‰ค0.007% but hydroxydaidzein lacks individual concentration limit. Use with caution pending final SCCS opinion. The EU classifies Hydroxydaidzein as "permitted". Safety rating: MODERATE.

Is Hydroxydaidzein allowed in the EU?

Hydroxydaidzein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxydaidzein do in cosmetics?

Hydroxydaidzein functions as: Antioxidant, skin conditioning, skin protecting. It is classified as a cosmetic ingredient in our database. CAS number: 485-63-2.

What is the Margin of Safety for Hydroxydaidzein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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