Hydroxypropyl Bistrimonium Diiodide

INCI: HYDROXYPROPYL BISTRIMONIUM DIIODIDE

CAS Number
123-47-7
Function
Antimicrobial — controls microorganism growth on skin
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not specifically restricted under 21 CFR; iodine-releasing agents are permitted in cosmetics

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Iodine-releasing antimicrobial with potential thyroid function concerns with chronic use; contraindicated for thyroid-disorder patients and those with povidone-iodine sensitivity; Annex V compliance must be confirmed

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxypropyl Bistrimonium Diiodide safe in cosmetics?

Iodine-releasing antimicrobial with potential thyroid function concerns with chronic use; contraindicated for thyroid-disorder patients and those with povidone-iodine sensitivity; Annex V compliance must be confirmed The EU classifies Hydroxypropyl Bistrimonium Diiodide as "permitted". Safety rating: MODERATE.

Is Hydroxypropyl Bistrimonium Diiodide allowed in the EU?

Hydroxypropyl Bistrimonium Diiodide EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyl Bistrimonium Diiodide do in cosmetics?

Hydroxypropyl Bistrimonium Diiodide functions as: Antimicrobial — controls microorganism growth on skin. It is classified as a cosmetic ingredient in our database. CAS number: 123-47-7.

What is the Margin of Safety for Hydroxypropyl Bistrimonium Diiodide?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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