Hydroxypropyl Cyclodextrin

CAS Number
128446-35-5
Function
Deodorizer; Softener and conditioner
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” GRAS status (FDA); not restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hydroxypropyl cyclodextrin is a safe cosmetic ingredient with GRAS status and excellent safety profile, permitted for use in both EU and US markets.

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Concern Level: Low

Frequently Asked Questions

Is Hydroxypropyl Cyclodextrin safe in cosmetics?

Hydroxypropyl cyclodextrin is a safe cosmetic ingredient with GRAS status and excellent safety profile, permitted for use in both EU and US markets. The EU classifies Hydroxypropyl Cyclodextrin as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropyl Cyclodextrin allowed in the EU?

Hydroxypropyl Cyclodextrin EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyl Cyclodextrin do in cosmetics?

Hydroxypropyl Cyclodextrin functions as: Deodorizer; Softener and conditioner. It is classified as a cosmetic ingredient in our database. CAS number: 128446-35-5.

What is the Margin of Safety for Hydroxypropyl Cyclodextrin?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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