Hydroxypropyl Methylcellulose Acetate/Succinate

INCI: HYDROXYPROPYL METHYLCELLULOSE ACETATE/SUCCINATE

CAS Number
71138-97-1
Function
Film forming, viscosity controlling, binder, emulsion stabilizer
Safety Rating
EXCELLENT

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” CIR Expert Panel: safe for use as cosmetic ingredients; parent celluloses have FDA GRAS status and OTC drug approval

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

HPMCAS is a cellulose derivative permitted for cosmetic use with excellent safety profile and adequate margin of safety.

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Concern Level: Low

Frequently Asked Questions

Is Hydroxypropyl Methylcellulose Acetate/Succinate safe in cosmetics?

HPMCAS is a cellulose derivative permitted for cosmetic use with excellent safety profile and adequate margin of safety. The EU classifies Hydroxypropyl Methylcellulose Acetate/Succinate as "permitted". Safety rating: EXCELLENT.

Is Hydroxypropyl Methylcellulose Acetate/Succinate allowed in the EU?

Hydroxypropyl Methylcellulose Acetate/Succinate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyl Methylcellulose Acetate/Succinate do in cosmetics?

Hydroxypropyl Methylcellulose Acetate/Succinate functions as: Film forming, viscosity controlling, binder, emulsion stabilizer. It is classified as a cosmetic ingredient in our database. CAS number: 71138-97-1.

What is the Margin of Safety for Hydroxypropyl Methylcellulose Acetate/Succinate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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