Hydroxypropyltrimonium Ascorbate

INCI: HYDROXYPROPYLTRIMONIUM ASCORBATE

CAS Number
Not widely published (cationic vitamin C derivative; verify via CosIng)
Function
Antioxidant, skin conditioning (cationic ascorbic acid derivative)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” no CFR restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Significant data gap with no CIR or SCCS assessment identified. Safety inferred from ascorbic acid's GRAS status and trimonium derivatives reviewed by CIR as safe when non-irritating. CPSR assessor should request full supplier safety dossier including HRIPT data.

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxypropyltrimonium Ascorbate safe in cosmetics?

Significant data gap with no CIR or SCCS assessment identified. Safety inferred from ascorbic acid's GRAS status and trimonium derivatives reviewed by CIR as safe when non-irritating. CPSR assessor should request full supplier safety dossier including HRIPT data. The EU classifies Hydroxypropyltrimonium Ascorbate as "permitted". Safety rating: MODERATE.

Is Hydroxypropyltrimonium Ascorbate allowed in the EU?

Hydroxypropyltrimonium Ascorbate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Ascorbate do in cosmetics?

Hydroxypropyltrimonium Ascorbate functions as: Antioxidant, skin conditioning (cationic ascorbic acid derivative). It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (cationic vitamin C derivative; verify via CosIng).

What is the Margin of Safety for Hydroxypropyltrimonium Ascorbate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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