Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate

INCI: HYDROXYPROPYLTRIMONIUM HYDROLYZED WHEAT PROTEIN/SILOXYSILICATE

CAS Number
Not assigned (complex copolymer)
Function
Hair conditioning (protein–silicone hybrid)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR MW restriction (≤ 3500 Da) applies to the protein portion

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Wheat protein MW restrictions apply; supplier must provide MW data for the protein portion specifically; silicone portion must be free of D4/D5 per EU REACH SVHCs; dual documentation required (protein MW and silicone purity).

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Concern Level: Moderate

Frequently Asked Questions

Is Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate safe in cosmetics?

Wheat protein MW restrictions apply; supplier must provide MW data for the protein portion specifically; silicone portion must be free of D4/D5 per EU REACH SVHCs; dual documentation required (protein MW and silicone purity). The EU classifies Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate as "permitted". Safety rating: MODERATE.

Is Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate allowed in the EU?

Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate do in cosmetics?

Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate functions as: Hair conditioning (protein–silicone hybrid). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (complex copolymer).

What is the Margin of Safety for Hydroxypropyltrimonium Hydrolyzed Wheat Protein/Siloxysilicate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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