Hydroxypropyltrimonium Lemon Protein

INCI: HYDROXYPROPYLTRIMONIUM LEMON PROTEIN

CAS Number
1857327-20-8 [^1_2]
Function
Humectant, hair conditioning, antistatic
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — not listed in 21 CFR 700 (prohibited) or restricted; no specific CIR monograph for this exact INCI

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Quaternized protein with potential for protein contact dermatitis at high molecular weight; pH stable 4–7 and temperature stable below 50°C; recommended use 0.5–5%; safety supported at concentrations ≤0.25% in leave-on formulations based on read-across from CIR trimonium assessments.

⚠️
Concern Level: Moderate

Frequently Asked Questions

Is Hydroxypropyltrimonium Lemon Protein safe in cosmetics?

Quaternized protein with potential for protein contact dermatitis at high molecular weight; pH stable 4–7 and temperature stable below 50°C; recommended use 0.5–5%; safety supported at concentrations ≤0.25% in leave-on formulations based on read-across from CIR trimonium assessments. The EU classifies Hydroxypropyltrimonium Lemon Protein as "permitted". Safety rating: MODERATE.

Is Hydroxypropyltrimonium Lemon Protein allowed in the EU?

Hydroxypropyltrimonium Lemon Protein EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxypropyltrimonium Lemon Protein do in cosmetics?

Hydroxypropyltrimonium Lemon Protein functions as: Humectant, hair conditioning, antistatic. It is classified as a cosmetic ingredient in our database. CAS number: 1857327-20-8 [^1_2].

What is the Margin of Safety for Hydroxypropyltrimonium Lemon Protein?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

📱

Is Hydroxypropyltrimonium Lemon Protein in Your Products?

Scan any product label with Piro — our free ingredient scanner. Point your camera at the ingredients list and get instant safety scores for every ingredient.

Try Piro Free →

Analyze Your Full Ingredient List

Paste any INCI list into the Decoder for instant safety analysis, or calculate the Margin of Safety for Hydroxypropyltrimonium Lemon Protein in your formulation.