Hydroxysteroid Oxidoreductase

INCI: HYDROXYSTEROID OXIDOREDUCTASE

CAS Number
Not assigned (enzyme — EC classification varies by specific type)
Function
Skin Conditioning Agent (enzyme-based; catalyzes oxidation-reduction of hydroxysteroids)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — no specific restrictions; no CIR monograph

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Enzyme ingredient with potential for allergenic response; purity and source organism must be documented; potential endocrine-activity concerns due to steroid substrate action; microbial contamination risk from fermentation-derived material; biotech origin documentation essential.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Hydroxysteroid Oxidoreductase safe in cosmetics?

Enzyme ingredient with potential for allergenic response; purity and source organism must be documented; potential endocrine-activity concerns due to steroid substrate action; microbial contamination risk from fermentation-derived material; biotech origin documentation essential. The EU classifies Hydroxysteroid Oxidoreductase as "permitted". Safety rating: MODERATE.

Is Hydroxysteroid Oxidoreductase allowed in the EU?

Hydroxysteroid Oxidoreductase EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hydroxysteroid Oxidoreductase do in cosmetics?

Hydroxysteroid Oxidoreductase functions as: Skin Conditioning Agent (enzyme-based; catalyzes oxidation-reduction of hydroxysteroids). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (enzyme — EC classification varies by specific type).

What is the Margin of Safety for Hydroxysteroid Oxidoreductase?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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