Excellent Cosmetic Ingredient

Hypericum Perforatum Flower/Leaf/Stem Extract

INCI: HYPERICUM PERFORATUM FLOWER/LEAF/STEM EXTRACT

CAS Number
84082-80-4 / EC 282-026-4 / CosIng Ref 83453 [^1_9]
Function
Skin conditioning — miscellaneous; antimicrobial
Safety Rating
EXCELLENT

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR concluded safe in the present practices of use and concentration; most-used variant (49 leave-on + 25 rinse-off products reported to VCRP)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Hypericum perforatum extract is permitted in both EU and US markets with adequate margin of safety. Hypericin content (0.06–0.4% in plant material) may cause phototoxicity at high concentrations; CIR cautions against cumulative botanical loading. Safety profile depends on extraction solvent and solids content (0.1–5%).

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Concern Level: Low

Regulatory Flags

plant-extract natural-origin

Frequently Asked Questions

Is Hypericum Perforatum Flower/Leaf/Stem Extract safe in cosmetics?

Hypericum perforatum extract is permitted in both EU and US markets with adequate margin of safety. Hypericin content (0.06–0.4% in plant material) may cause phototoxicity at high concentrations; CIR cautions against cumulative botanical loading. Safety profile depends on extraction solvent and solids content (0.1–5%). The EU classifies Hypericum Perforatum Flower/Leaf/Stem Extract as "permitted". Safety rating: EXCELLENT.

Is Hypericum Perforatum Flower/Leaf/Stem Extract allowed in the EU?

Hypericum Perforatum Flower/Leaf/Stem Extract EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Hypericum Perforatum Flower/Leaf/Stem Extract do in cosmetics?

Hypericum Perforatum Flower/Leaf/Stem Extract functions as: Skin conditioning — miscellaneous; antimicrobial. It is classified as a cosmetic ingredient in our database. CAS number: 84082-80-4 / EC 282-026-4 / CosIng Ref 83453 [^1_9].

What is the Margin of Safety for Hypericum Perforatum Flower/Leaf/Stem Extract?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hypericum Perforatum Flower/Leaf/Stem Extract compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
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