Moderate Cosmetic Ingredient

Hyssopus Officinalis Flower/Leaf/Stem Oil

INCI: HYSSOPUS OFFICINALIS FLOWER/LEAF/STEM OIL

CAS Number
84603-66-7 [^1_3]
Function
Fragrance, skin conditioning
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status restricted
EU Max Conc. 0.04%
🇺🇸 US Status permitted
US Notes Permitted — GRAS under FDA 21 CFR Part 182; IFRA guidelines apply

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
moderate

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains pinocamphone (11–18%) and isopinocamphone (22–29%) — both are neurotoxic ketones capable of inducing seizures at elevated doses; may contain methyleugenol (IARC Group 2B carcinogen); contraindicated in pregnancy, breastfeeding, children under 2; Tisserand & Young max dermal use 0.3%; aspiration toxicity Cat. 1

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Concern Level: High

Regulatory Flags

plant-oil fragrance-component

Frequently Asked Questions

Is Hyssopus Officinalis Flower/Leaf/Stem Oil safe in cosmetics?

Contains pinocamphone (11–18%) and isopinocamphone (22–29%) — both are neurotoxic ketones capable of inducing seizures at elevated doses; may contain methyleugenol (IARC Group 2B carcinogen); contraindicated in pregnancy, breastfeeding, children under 2; Tisserand & Young max dermal use 0.3%; aspiration toxicity Cat. 1 The EU classifies Hyssopus Officinalis Flower/Leaf/Stem Oil as "restricted". Safety rating: MODERATE.

Is Hyssopus Officinalis Flower/Leaf/Stem Oil allowed in the EU?

Hyssopus Officinalis Flower/Leaf/Stem Oil EU regulatory status: restricted. Maximum allowed concentration: 0.04%. This is based on EU Regulation 1223/2009 and its amendments.

What does Hyssopus Officinalis Flower/Leaf/Stem Oil do in cosmetics?

Hyssopus Officinalis Flower/Leaf/Stem Oil functions as: Fragrance, skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: 84603-66-7 [^1_3].

What is the Margin of Safety for Hyssopus Officinalis Flower/Leaf/Stem Oil?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Hyssopus Officinalis Flower/Leaf/Stem Oil compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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