Indol Acetyl Phenylalanine

INCI: INDOL ACETYL PHENYLALANINE

CAS Number
Not widely published (amino acid conjugate of indole-3-acetic acid with L-phenylalanine)
Function
Skin conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not prohibited or restricted under 21 CFR

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Contains indole moiety; no SCCS opinion; no published genotoxicity or repeat-dose dermal data; CPSR assessor will require dermal irritation, sensitization (DPRA/KeratinoSens), and genotoxicity (Ames) testing.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Indol Acetyl Phenylalanine safe in cosmetics?

Contains indole moiety; no SCCS opinion; no published genotoxicity or repeat-dose dermal data; CPSR assessor will require dermal irritation, sensitization (DPRA/KeratinoSens), and genotoxicity (Ames) testing. The EU classifies Indol Acetyl Phenylalanine as "restricted". Safety rating: MODERATE.

Is Indol Acetyl Phenylalanine allowed in the EU?

Indol Acetyl Phenylalanine EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Indol Acetyl Phenylalanine do in cosmetics?

Indol Acetyl Phenylalanine functions as: Skin conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not widely published (amino acid conjugate of indole-3-acetic acid with L-phenylalanine).

What is the Margin of Safety for Indol Acetyl Phenylalanine?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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