Inositol Hexaniacinate Hexaascorbate

INCI: INOSITOL HEXANIACINATE HEXAASCORBATE

CAS Number
Not assigned (parent inositol hexanicotinate: 6556-11-2)
Function
Antioxidant, Skin Conditioning
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted โ€” not on FDA prohibited/restricted list; parent inositol is GRAS (21 CFR 184.1370)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Data-poor ingredient with no CIR monograph for this specific salt. Parent inositol reviewed by CIR as safe at concentrations โ‰ค4% in leave-on products. Niacin flush possible at high concentrations if significant hydrolysis occurs on skin. Requires supplier Certificate of Analysis and supporting toxicology dossier for CPSR.

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Concern Level: Moderate

Frequently Asked Questions

Is Inositol Hexaniacinate Hexaascorbate safe in cosmetics?

Data-poor ingredient with no CIR monograph for this specific salt. Parent inositol reviewed by CIR as safe at concentrations โ‰ค4% in leave-on products. Niacin flush possible at high concentrations if significant hydrolysis occurs on skin. Requires supplier Certificate of Analysis and supporting toxicology dossier for CPSR. The EU classifies Inositol Hexaniacinate Hexaascorbate as "permitted". Safety rating: MODERATE.

Is Inositol Hexaniacinate Hexaascorbate allowed in the EU?

Inositol Hexaniacinate Hexaascorbate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Inositol Hexaniacinate Hexaascorbate do in cosmetics?

Inositol Hexaniacinate Hexaascorbate functions as: Antioxidant, Skin Conditioning. It is classified as a cosmetic ingredient in our database. CAS number: Not assigned (parent inositol hexanicotinate: 6556-11-2).

What is the Margin of Safety for Inositol Hexaniacinate Hexaascorbate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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