Interleukin-1 Beta Antagonist

INCI: INTERLEUKIN-1 BETA ANTAGONIST

CAS Number
Not assigned in CosIng (biotech/recombinant protein; some peptide fragments carry CAS 106021-96-9)
Function
Skin protecting, skin conditioning (anti-inflammatory biotech active)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status permitted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Not restricted by FDA; manufacturer bears safety-substantiation burden under MoCRA

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
negligible
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Novel biotech ingredient with sparse toxicological review; no CIR or SCCS opinion; requires robust in-house safety dossier for EU responsible-person file

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Concern Level: Moderate

Frequently Asked Questions

Is Interleukin-1 Beta Antagonist safe in cosmetics?

Novel biotech ingredient with sparse toxicological review; no CIR or SCCS opinion; requires robust in-house safety dossier for EU responsible-person file The EU classifies Interleukin-1 Beta Antagonist as "permitted". Safety rating: MODERATE.

Is Interleukin-1 Beta Antagonist allowed in the EU?

Interleukin-1 Beta Antagonist EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Interleukin-1 Beta Antagonist do in cosmetics?

Interleukin-1 Beta Antagonist functions as: Skin protecting, skin conditioning (anti-inflammatory biotech active). It is classified as a cosmetic ingredient in our database. CAS number: Not assigned in CosIng (biotech/recombinant protein; some peptide fragments carry CAS 106021-96-9).

What is the Margin of Safety for Interleukin-1 Beta Antagonist?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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