Isobutyl Myristate

INCI: ISOBUTYL MYRISTATE

CAS Number
Verify with supplier (ester of isobutanol + myristic acid / tetradecanoic acid)
Function
Skin conditioning — emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR Expert Panel: safe in present practices of use and concentration when formulated to be non-irritating (2013 Amended Assessment)

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Formulate to be non-irritating per CIR stipulation; myristate esters have potential comedogenicity (3-4/5 on comedogenicity scale) and may enhance penetration of co-formulated actives—verify margin of safety of other ingredients if penetration enhancement occurs.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Isobutyl Myristate safe in cosmetics?

Formulate to be non-irritating per CIR stipulation; myristate esters have potential comedogenicity (3-4/5 on comedogenicity scale) and may enhance penetration of co-formulated actives—verify margin of safety of other ingredients if penetration enhancement occurs. The EU classifies Isobutyl Myristate as "permitted". Safety rating: GOOD.

Is Isobutyl Myristate allowed in the EU?

Isobutyl Myristate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Myristate do in cosmetics?

Isobutyl Myristate functions as: Skin conditioning — emollient. It is classified as a cosmetic ingredient in our database. CAS number: Verify with supplier (ester of isobutanol + myristic acid / tetradecanoic acid).

What is the Margin of Safety for Isobutyl Myristate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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