Isobutyl Oleate

INCI: ISOBUTYL OLEATE

CAS Number
Verify with supplier (ester of isobutanol + oleic acid)
Function
Skin conditioning — emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — supported by CIR alkyl ester group assessment; butyl oleate analog has dermal LD50 >5 g/kg and oral LD50 >5 g/kg in animal studies

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Formulate to be non-irritating; penetration enhancement effect documented for oleate esters — reassess MoS of co-formulated ingredients; oleic acid moiety is unsaturated — oxidative stability considerations for shelf life

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Concern Level: Low

Frequently Asked Questions

Is Isobutyl Oleate safe in cosmetics?

Formulate to be non-irritating; penetration enhancement effect documented for oleate esters — reassess MoS of co-formulated ingredients; oleic acid moiety is unsaturated — oxidative stability considerations for shelf life The EU classifies Isobutyl Oleate as "permitted". Safety rating: GOOD.

Is Isobutyl Oleate allowed in the EU?

Isobutyl Oleate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Oleate do in cosmetics?

Isobutyl Oleate functions as: Skin conditioning — emollient. It is classified as a cosmetic ingredient in our database. CAS number: Verify with supplier (ester of isobutanol + oleic acid).

What is the Margin of Safety for Isobutyl Oleate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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