Isobutyl Palmitate

INCI: ISOBUTYL PALMITATE

CAS Number
Verify with supplier (ester of isobutanol + palmitic acid / hexadecanoic acid)
Function
Skin conditioning — emollient
Safety Rating
GOOD

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Permitted — CIR Expert Panel: safe as used when formulated to be non-irritating

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
adequate
Dermal Absorption
negligible
Sensitization
none

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Formulate to be non-irritating; isobutyl palmitate acts as a lipid-layer penetration enhancer — verify effect on co-formulated actives.

⚠️
Concern Level: Low

Frequently Asked Questions

Is Isobutyl Palmitate safe in cosmetics?

Formulate to be non-irritating; isobutyl palmitate acts as a lipid-layer penetration enhancer — verify effect on co-formulated actives. The EU classifies Isobutyl Palmitate as "permitted". Safety rating: GOOD.

Is Isobutyl Palmitate allowed in the EU?

Isobutyl Palmitate EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isobutyl Palmitate do in cosmetics?

Isobutyl Palmitate functions as: Skin conditioning — emollient. It is classified as a cosmetic ingredient in our database. CAS number: Verify with supplier (ester of isobutanol + palmitic acid / hexadecanoic acid).

What is the Margin of Safety for Isobutyl Palmitate?

adequate The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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