Moderate Cosmetic Ingredient

Isoceteth-12

INCI: ISOCETETH-12

CAS Number
Not confirmed from search results (follows same chemical class as Isoceteth-10, CAS 69364-63-2, but with 12 mol EO)
Function
Surfactant - Cleansing; Surfactant - Emulsifying (same functional class as Isoceteth-10)
Safety Rating
MODERATE

Regulatory Status

🇪🇺 EU Status permitted
🇺🇸 US Status permitted
US Notes Allowed - no specific prohibition or restriction

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Identical class concerns as Isoceteth-10: residual 1,4-dioxane and ethylene oxide from ethoxylation. Higher ethoxylation degree (12 vs. 10) means slightly higher HLB and water solubility. PEG ether of branched C16 alcohol with 12 moles of ethylene oxide. Higher HLB than Isoceteth-10, making it more hydrophilic and better suited for O/W emulsions or solubilization of oil-soluble actives into aqueous phases

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Concern Level: Moderate

Frequently Asked Questions

Is Isoceteth-12 safe in cosmetics?

Identical class concerns as Isoceteth-10: residual 1,4-dioxane and ethylene oxide from ethoxylation. Higher ethoxylation degree (12 vs. 10) means slightly higher HLB and water solubility. PEG ether of branched C16 alcohol with 12 moles of ethylene oxide. Higher HLB than Isoceteth-10, making it more hydrophilic and better suited for O/W emulsions or solubilization of oil-soluble actives into aqueous phases The EU classifies Isoceteth-12 as "permitted". Safety rating: MODERATE.

Is Isoceteth-12 allowed in the EU?

Isoceteth-12 EU regulatory status: permitted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isoceteth-12 do in cosmetics?

Isoceteth-12 functions as: Surfactant - Cleansing; Surfactant - Emulsifying (same functional class as Isoceteth-10). It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from search results (follows same chemical class as Isoceteth-10, CAS 69364-63-2, but with 12 mol EO).

What is the Margin of Safety for Isoceteth-12?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

Compliance Tools

Check Isoceteth-12 compliance across multiple jurisdictions:

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Ingredient Decoder
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82 Allergen Checker
Check for EU declarable fragrance allergens
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Substance Compliance
Check compliance across 55 jurisdictions
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MoS Calculator
Calculate Margin of Safety using SCCS methodology
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Heavy Metal Limits
Compare limits across jurisdictions

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