Isopropyl-alpha-Methylcinnamaldehyde

CAS Number
Verify with supplier โ€” likely in the region of cinnamaldehyde derivatives (parent: cinnamal CAS 104-55-2)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Permitted with no specific CFR restriction, but IFRA may impose use limits depending on isomer.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
moderate
Sensitization
high

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

High sensitization concern requiring HRIPT data, RIFM assessment, concentration limits aligned with IFRA standards, and mandatory label declaration if allergen threshold exceeded (0.001% leave-on / 0.01% rinse-off).

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Concern Level: High

Regulatory Flags

potential-allergen fragrance-component

Frequently Asked Questions

Is Isopropyl-alpha-Methylcinnamaldehyde safe in cosmetics?

High sensitization concern requiring HRIPT data, RIFM assessment, concentration limits aligned with IFRA standards, and mandatory label declaration if allergen threshold exceeded (0.001% leave-on / 0.01% rinse-off). The EU classifies Isopropyl-alpha-Methylcinnamaldehyde as "restricted". Safety rating: MODERATE.

Is Isopropyl-alpha-Methylcinnamaldehyde allowed in the EU?

Isopropyl-alpha-Methylcinnamaldehyde EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What is the Margin of Safety for Isopropyl-alpha-Methylcinnamaldehyde?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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