Isostearamidopropyl Dimethylamine Gluconate

INCI: ISOSTEARAMIDOPROPYL DIMETHYLAMINE GLUCONATE

CAS Number
Not confirmed from available search results. Likely a salt of isostearamidopropyl dimethylamine with gluconic acid.
Function
Antistatic, hair conditioning agent, emulsifier (cationic conditioning)
Safety Rating
MODERATE

Regulatory Status

๐Ÿ‡ช๐Ÿ‡บ EU Status restricted
๐Ÿ‡บ๐Ÿ‡ธ US Status permitted
US Notes Allowed. CIR Panel concluded fatty acid amidopropyl dimethylamines are safe when formulated to be non-sensitizing.

For full compliance data across 55 jurisdictions, use the Substance Compliance tool.

Safety Data

Margin of Safety (MoS)
not established
Dermal Absorption
low
Sensitization
low

Calculate MoS for your specific formulation with the MoS Calculator.

Expert Verdict

Potential for skin sensitization; must control amidoamine and free amine impurity levels. Gluconate counterion is generally benign. Nitrosamine controls apply to the tertiary amine moiety.. Cationic conditioning agent. The gluconate salt form improves water solubility and formulation compatibility versus free-base dimethylamine forms. Provides substantivity to damaged/negatively-charged hair.

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Concern Level: Moderate

Regulatory Flags

potential-allergen

Frequently Asked Questions

Is Isostearamidopropyl Dimethylamine Gluconate safe in cosmetics?

Potential for skin sensitization; must control amidoamine and free amine impurity levels. Gluconate counterion is generally benign. Nitrosamine controls apply to the tertiary amine moiety.. Cationic conditioning agent. The gluconate salt form improves water solubility and formulation compatibility versus free-base dimethylamine forms. Provides substantivity to damaged/negatively-charged hair. The EU classifies Isostearamidopropyl Dimethylamine Gluconate as "restricted". Safety rating: MODERATE.

Is Isostearamidopropyl Dimethylamine Gluconate allowed in the EU?

Isostearamidopropyl Dimethylamine Gluconate EU regulatory status: restricted. This is based on EU Regulation 1223/2009 and its amendments.

What does Isostearamidopropyl Dimethylamine Gluconate do in cosmetics?

Isostearamidopropyl Dimethylamine Gluconate functions as: Antistatic, hair conditioning agent, emulsifier (cationic conditioning). It is classified as a cosmetic ingredient in our database. CAS number: Not confirmed from available search results. Likely a salt of isostearamidopropyl dimethylamine with gluconic acid..

What is the Margin of Safety for Isostearamidopropyl Dimethylamine Gluconate?

not established The Margin of Safety (MoS) is calculated using SCCS methodology. A MoS above 100 is generally considered safe. Use the MoS Calculator tool to calculate MoS for your specific formulation and product category.

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